Origins of the Black Death

We have been seeing some marvellous acts of bio-detectives in recent years. In yet another monumental feat of locating the proverbial needle in the haystack, scientists of the Eberhard Karls University of Tübingen have unearthed the origins of the bubonic plague of the mid-14th century.

In a paper published yesterday in the prestigious journal Nature, Spyrou et al. describe how DNA sequences of samples from seven individuals exhumed from two of the cemeteries in Kara-Djigach and Burana of the modern-day Kyrgistan.

The team collected the tooth samples from Peter the Great Museum of Anthropology and Ethnography in St Petersburg. The specimens were excavated between 1885 and 1892. The tombstone inscriptions suggest that the victims were dead between 1338 and 1339. DNA extractions were done from the tooth powder using standard extraction reagents, and voila: they see DNA sections of Yersinia pestis (Y. pestis), the bacterium responsible for killing about 60% of the population of western Eurasia!

What is more? The study identified the DNA as the common ancestor to the bacteria strains that ran havoc in central Eurasia.

The source of the Black Death in fourteenth-century central Eurasia: Nature