Family-Wise Error Rate

Imagine a fair coin is tossed 10 times to test the hypothesis, H0: the coin is unbiased. The coin likely lands on heads (or tails) in about 5 (or 4, 3, 2) of those. If it landed 4 times on heads and 6 in tails, we can do a simple chi-squared test to verify.
chi-squared = (4 – 5)2 /5 + (4 – 5)2 /5 = 0.4. 0.4 is too low; we can’t reject null

But what happens if all the tosses land on tails?
chi-squared = (0 – 5)2 /5 + (10 – 5)2 /5 = 10. We reject at 99% confidence level. We know the probability of this happening is (1/2)10 = 1/1024.

chisq.test(c(0,10),p=c(0.5,0.5))
	Chi-squared test for given probabilities

data:  c(0, 10)
X-squared = 10, df = 1, p-value = 0.001565

What about 1024 players, each having a (fair) coin toss 10 times each?

1 - dbinom(0, 1024, 1/1024)
0.63

In other words, there is a possibility that one person will reject the null hypothesis and conclude that the coin is based! An incorrect rejection of a null hypothesis or a false positive result. In other words, if we test a lot (a family) of hypotheses, there is a high probability of getting one very small p-value by chance.