You tell me smoking causes lung cancer. I know several of my friends who smokes but never got cancer. How do you explain?
Suppose 90% of lung cancer patients are smokers and 20% of people with no lung cancer also smoke. What is the chance that a smoker has cancer? To estimate the answer, we should first know the probability of lung cancer in society. Suppose it is 0.1%.
So, the probability of a random smoker having cancer is 0.44%. So what about non-smokers having lung cancer?
It is 0.013%. Therefore, a smoker is 0.44/0.013 = 35 times more likely to get cancer.